This pathology got its name in honor of neurosurgeons who, in different years and independently of each other, revealed similar manifestations of the disease and associated them with structural disorders in the brain of patients. The disease is named after Walter Dandy, who first described it in 1921, and Earl Walker, who made his discovery 23 years later.
As with most fetal anomalies, it is not known for certain why Dandy Walker syndrome occurs. At this stage of the development of medicine, it is generally accepted that the main reasons that lead to buy naltrexone online development are. Viral diseases in the first trimester of pregnancy. Rubella and cytomegalovirus transferred by a pregnant woman. Diabetes mellitus in a future mother. Chronic alcoholism. Genetic background.
Often, Dandy Walker syndrome is diagnosed on a screening ultrasound examination of the fetus in the first trimester. In most cases, pathology occurs against the background of complete well-being, without any of the above messages. With a timely ultrasound diagnosis of a pregnant woman and the detection of Walker's syndrome, it is recommended to terminate the pregnancy for medical reasons. Despite the burden of making a decision that falls on the parents, they make the final decision.
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In the modern classification of diseases of the ICD 10, Dandy Walker syndrome has the code Q03.1 atresia of generic revia of Magendie and Lushko. Dandy Walker syndrome occurs with a frequency of 1 case per 25,000 children, girls are more often affected. The risk of having a second child with Walker syndrome in the same family in the absence of a genetic component varies from 2 to 7% according to various sources.
There are several main ultrasound signs of Dandy Walker syndrome, which can be determined already during a screening study at 21-23 weeks of gestation. During this period, an anomaly of intrauterine development can be suspected based on the detection of the following symptoms in the fetus. At later stages of pregnancy, from about 31 weeks, in addition to these signs, the fetus will also be visible.
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The severity of the clinical picture in Dandy Walker syndrome is very diverse. The disease can proceed both in extremely severe forms and lead to the death of naltrexone pills, or practically not make itself felt either by external or internal manifestations. In about 50% of cases, the child is slightly behind in psichomotor and cognitive development. However, intrauterine development anomalies, as a rule, occur in groups, which significantly worsens both the quality of life of the child and the prognosis for the future.
The main symptom in Walker's syndrome, which can be determined visually, is hydrocephalus, which can be expressed to buy revia online. In such children, a large fontanel swells, the baby is capricious, he has high reflexes, eye symptoms are pronounced, episodes of respiratory arrest may also be noted, it may be pathological. At this age, it is impossible to determine the presence of cerebellar symptoms in a baby. Also, they are characterized not only by the bulging of the fontanel, but also by its long non-overgrowth, divergence of the seams. All these visual manifestations arise as a result of an increase in the insolvency of the infant's liquorodynamic system.
As the child grows, the presence of pathological cerebellar symptoms can be determined. It is also worth noting that, despite the triad of pathomorphological signs, such symptoms occur only in 25-30% of patients with this pathology. Violation of psychomotor development can also be expressed to varying degrees, this is more related to the severity of revia to the central nervous system. In severe cases, Dandy Walker syndrome may be accompanied by convulsions. The severity of the condition of a small patient is due to congenital pathology not so much of the central nervous system as of other organs and systems, this may be damage to the heart and kidneys.